HISTOLOGICAL CHANGES OF THE PANCREAS IN DIABETES MELLITUS AND PANCREATITIS.
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This paper describes the histological alterations that occur in the pancreas during diabetes mellitus and pancreatitis. In diabetes mellitus, characteristic changes include degeneration and reduction of pancreatic islet cells, hyalinization of blood vessels, and fibrosis of the interstitial tissue. In chronic pancreatitis, inflammatory infiltration, acinar cell atrophy, ductal dilation, and fibrotic replacement of the parenchyma are observed. The comparative analysis of these conditions highlights how both endocrine and exocrine components of the pancreas are affected, leading to impaired metabolic and digestive functions. Understanding these histological features is essential for accurate diagnosis and for developing effective therapeutic approaches.
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