OBTAINING OF CHITIN AND CHITOSAN FROM THE NARROW-CLAWED CRAYFISH (PONTASTACUS LEPTODACTYLUS) AND THEIR CHARACTERIZATION BY IR SPECTROSCOPY
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Abstract
Chitosan is a promising auxiliary substance in pharmaceutical technology due to its wide range of shaping and functional properties. A significant reserve of raw material for obtaining chitosan is represented by stocks of the narrow-clawed lake crayfish. Chitosan obtained from narrow-clawed crayfish was studied in order to evaluate its physicochemical and technological properties for the development of pharmaceutical dosage forms. Comparative analysis of the physicochemical characteristics of chitosan derived from narrow-clawed crayfish, bee podmore, and silkworm pupae demonstrated their similar chemical nature and molecular structure. The molecular weight of the obtained chitosan was determined by the viscometric method, while the degree of acetylation was assessed conductometrically. The structures of chitin and chitosan were analyzed using IR spectroscopy.
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