HISTOGENESIS OF THE FEMALE REPRODUCTIVE SYSTEM
DOI:
https://doi.org/10.55640/Keywords:
histogenesis, embryology, ovary, Müllerian duct, uterine tube, uterus, cervix, vagina, primordial germ cells.Abstract
Histogenesis of the female reproductive system describes how embryonic cell populations differentiate into the tissues of the ovaries, uterine tubes, uterus, cervix, vagina, and external genitalia. This development is coordinated by germ-cell migration, gonadal ridge formation, ductal remodeling, and region-specific epithelial–mesenchymal interactions. In the absence of testis-determining signals, the indifferent gonad differentiates into an ovary, the Müllerian ducts persist to form the uterine tubes, uterus, and cervix, and the urogenital sinus contributes to the lower vagina.
Downloads
References
1.Moore K. L., Persaud T. V. N., Torchia M. G. The Developing Human: Clinically Oriented Embryology. – 11th ed. – Edinburgh: Elsevier, 2020. – 490 p. searchworks.stanford.edu
2.Sadler T. W. Langman’s Medical Embryology. – 14th ed. – Philadelphia: Wolters Kluwer, 2019. – 432 p. catalogue.umu.ac.ug
3.Schoenwolf G. C., Bleyl S. B., Brauer P. R., Francis-West P. H. Larsen’s Human Embryology. – 6th ed. – Philadelphia: Elsevier, 2021. – 548 p. WorldCat
4.Mullen R. D., Behringer R. R. Molecular genetics of Müllerian duct formation, regression and differentiation // Sexual Development. – 2014. – Vol. 8, No. 5. – P. 281–296. – DOI: 10.1159/000364935. PubMed
5.Grive K. J., Freiman R. N. The developmental origins of the mammalian ovarian reserve // Development. – 2015. – Vol. 142, No. 15. – P. 2554–2563. – DOI: 10.1242/dev.125211.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

