HOLMIUM LASER ENUCLEATION OF THE PROSTATE VERSUS TURP AND OPEN PROSTATECTOMY FOR BENIGN PROSTATIC HYPERPLASIA: A SYSTEMATIC REVIEW
Article Sidebar
Main Article Content
Abstract
Benign prostatic hyperplasia (BPH) is one of the most prevalent urological conditions affecting aging men and represents a major cause of lower urinary tract symptoms (LUTS). Surgical intervention is indicated when conservative and pharmacological treatments fail. Traditionally, transurethral resection of the prostate (TURP) has been considered the surgical gold standard for moderate-sized prostates, while open prostatectomy (OP) has been reserved for large glands. Over the past two decades, holmium laser enucleation of the prostate (HoLEP) has emerged as a minimally invasive, size-independent alternative. This systematic review evaluates and compares HoLEP, TURP, and OP in terms of efficacy, safety, perioperative outcomes, long-term durability, and complications. Current evidence suggests that HoLEP provides equivalent or superior functional outcomes with reduced morbidity and retreatment rates, positioning it as a preferred surgical option for BPH when expertise is available.
Downloads
Article Details
Section
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.
How to Cite
References
1.CHRONIC PROSTATITIS: ETIOLOGY AND TREATMENT. (2025). International Journal of Medical Sciences, 5(12), 729-733. https://doi.org/10.55640/
2. COMPARISON OF SURGICAL TECHNIQUES FOR BENIGN PROSTATIC HYPERPLASIA: OUTCOMES AND INNOVATIONS. (2025). International Journal of Medical Sciences, 5(11), 551-554. https://doi.org/10.55640/
3. Mansurov Sardor Vali o’g’li. (2025). Neuro-Oncology in Transition: Molecular Classification and Emerging Therapies for Brain Tumors. International Journal of Integrative and Modern Medicine, 3(10), 233–237. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/2235
4. o’g’li, M. S. V. (2025). ESOPHAGEAL CANCER: EPIDEMIOLOGY, PATHOGENESIS, AND MODERN APPROACHES TO MANAGEMENT. International Journal of Cognitive Neuroscience and Psychology, 3(9), 59–64. Retrieved from https://medicaljournals.eu/index.php/IJCNP/article/view/2127
5. Mansurov Sardor Vali o'g'li. (2025). RECENT DEVELOPMENTS IN THE DIAGNOSIS AND TREATMENT OF HEPATITIS: A GLOBAL PERSPECTIVE. https://doi.org/10.5281/zenodo.15478708
6. Mansurov Sardor Vali o'g'li. (2025). URINARY BLADDER CANCER. https://doi.org/10.5281/zenodo.15227539
7. Mansurov Sardor Vali o'g'li. (2025). ACUTE KIDNEY INJURY: ETIOLOGY AND TREATMENT. https://doi.org/10.5281/zenodo.15070424
8. Mansurov Sardor Vali o'g'li. (2025). EPIDEMIOLOGY AND TREATMENT OF RENAL CELL CARCINOMA: IDENTIFYING KEY RISK FACTORS. https://doi.org/10.5281/zenodo.14909826
9. PROSTATE CANCER: PATHOLOGY AND TREATMENT. (2024). International Bulletin of Medical Sciences and Clinical Research, 4(11), 65-70. https://doi.org/10.37547/
10. Mansurov Sardor Vali o’g’li, KIDNEY CANCER: EPIDEMIOLOGY AND TREATMENT , EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE: Vol. 4 No. 11 (2024): European Journal of Modern Medicine and Practice
https://inovatus.es/index.php/ejmmp/article/view/4509
11. Mansurov Sardor Vali o’g’li, SQUAMOUS CELL CARCINOMA OF THE PENIS: EPIDEMIOLOGY AND TREATMENT , EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE: Vol. 4 No. 10 (2024): European Journal of Modern Medicine and Practice https://inovatus.es/index.php/ejmmp/article/view/4245
12. Valiyevich, M. S. . (2024). Specific Morphofunctional Characteristics of the Kidney Caused by Brain Damage in Various Emergency Situations. Research Journal of Trauma and Disability Studies, 3(4), 286–289. Retrieved from http://journals.academiczone.net/index.php/rjtds/article/view/2628
13.Bahromov Bekzod Shavkatovich. (2025). UROLITHIASIS: EPIDEMIOLOGY AND RISK FACTORS. https://doi.org/10.5281/zenodo.15070401
14.ANESTHESIOLOGICAL CARE AND INTENSIVE CARE OF GERONTOLOGICAL PATIENTS IN UROLOGY. (2025). International Journal of Medical Sciences, 5(02), 381-384. https://doi.org/10.55640/
15. SOME PROBLEMS OF UROLOGY IN NEPHROLOGY. (2024). International Journal of Medical Sciences, 4(12), 127-130. https://doi.org/10.55640/
16. PREVENTION OF INTRAOPERATIVE COMPLICATIONS OF ENDOVIDEOSURGICAL INTERVENTIONS IN UROLOGY. (2024). International Journal of Medical Sciences, 4(11), 292-295. https://doi.org/10.55640/
17. ПУТИ УЛУЧШЕНИЯ КАЧЕСТВА НЕОТЛОЖНОЙ ПОМОЩИ БОЛЬНЫМ УРЕТЕРОЛИТИАЗОМ. (2024). International Journal of Medical Sciences, 4(10), 135-138. https://doi.org/10.55640/
18. Bаhrоmоv Bekzоd Shаvkаtоvich. (2024). Urinary Tract Infection Gonorrhea. SCIENTIFIC JOURNAL OF APPLIED AND MEDICAL SCIENCES, 3(5), 515–517. Retrieved from https://sciencebox.uz/index.php/amaltibbiyot/article/view/10804
19. Shаvkаtоvich B. B. . (2024). Urinаry Trаct Infectiоns. Research Journal of Trauma and Disability Studies, 3(4), 249–251. Retrieved from https://journals.academiczone.net/index.php/rjtds/article/view/2602
20. Bahromov Bekzod Shavkatovich. (2025). PROSTATE CANCER: EPIDEMIOLOGY, RISK FACTORS, DIAGNOSIS. https://doi.org/10.5281/zenodo.15242564
21. URINARY STONE DISEASE: ETIOLOGY, PATHOGENESIS, AND TREATMENT. (2025). International Journal of Medical Sciences, 5(11), 456-458. https://doi.org/10.55640/
22. URINARY TRACT INFECTION (UTI): ETIOLOGY, PATHOGENESIS, DIAGNOSIS, AND TREATMENT. (2025). International Journal of Medical Sciences, 5(12), 735-738. https://doi.org/10.55640/
23. Bahromov Bekzod Shavkatovich. (2025). RISK FACTORS AND DIAGNOSIS OF KIDNEY STONE. https://doi.org/10.5281/zenodo.15515734
24. Shavkatovich, B. B. (2025). UROLITHIASIS: ETIOLOGY AND DIAGNOSTIC APPROACHES. International Journal of Cognitive Neuroscience and Psychology, 3(9), 39–43. Retrieved from https://medicaljournals.eu/index.php/IJCNP/article/view/2124
25. Bahromov Bekzod Shavkatovich. (2025). BENIGN PROSTATIC HYPERPLASIA (BPH). International Journal of Integrative and Modern Medicine, 3(10), 247–250. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/2238
26. ACUTE PROSTATITIS: ETIOLOGY, PATHOPHYSIOLOGY, CLINICAL PRESENTATION, DIAGNOSTIC APPROACH, AND CONTEMPORARY MANAGEMENT. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(01), 806-812. https://doi.org/10.55640/
27. MODERN TREATMENT APPROACHES FOR URINARY STONE DISEASE (UROLITHIASIS). (2026). Journal of Multidisciplinary Sciences and Innovations, 5(01), 802-805. https://doi.org/10.55640/