HISTOSTRUCTURAL CHANGES OF THYROID FOLLICLES IN HYPERTHYROIDISM

Authors

  • Ahmedova Lolakhon Abdulhamidovna Andijan State Medical Institute, Uzbekistan

DOI:

https://doi.org/10.55640/

Keywords:

thyroid gland, thyroid follicles, hyperthyroidism, histology, colloid depletion, follicular epithelium.

Abstract

This study examines histostructural alterations of thyroid follicles in hyperthyroidism and evaluates how these morphological changes correlate with the gland’s functional hyperactivity. Detailed microscopic analysis demonstrates that hyperthyroidism is characterized by follicular epithelial hypertrophy, papillary infoldings, colloid depletion, and increased vascularization. These findings highlight the structural basis of excessive thyroid hormone production and contribute to a deeper understanding of the disease’s pathophysiology.

References

1.Baloch ZW, LiVolsi VA. The pathology of hyperthyroidism. Front Endocrinol (Lausanne). 2018;9:737

2.My Endo Consult. Histology of Graves’ disease [Internet]. 2025 [cited 2025]. Available from: MyEndoConsult website.

3.University of Utah WebPath. Endocrine pathology – hyperthyroidism and Graves disease [Internet]. 2025 [cited 2025]. Available from: WebPath – Endocrine Pathology.

4.National Toxicology Program. Thyroid gland, follicular cell – hypertrophy and hyperplasia. Nonneoplastic lesion atlas [Internet]. 2013 [cited 2025].

5.Patholines. Hyperthyroidism – histopathology and diagnostic features [Internet]. 2023 [cited 2025]. Available from: Patholines.org.

6.WebPathology. Graves disease – diffuse toxic goiter [Internet]. 2025 [cited 2025]. Available from: WebPathology – Thyroid Hyperplasia section. Nga ME, Soon G. Thyroid pathology notes based on Robbins and Cotran. NUS Pathweb – Thyroid one-page summary [Internet]. 2024 [cited 2025].

7.Kumar V, Abbas AK, Aster JC. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Philadelphia: Elsevier; 2021. (chapter on thyroid gland and hyperthyroidism).

8.Kenhub. Histology of the thyroid gland – follicles, colloid and vasculature [Internet]. 2023 [cited 2025]. Available from: Kenhub.com.

9.Lloyd RV, Osamura RY, Klöppel G, Rosai J, editors. WHO Classification of Tumours of Endocrine Organs. 4th ed. Lyon: IARC; 2017. (sections on diffuse toxic goiter and thyroid hyperplasia).

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Published

2025-12-01

How to Cite

HISTOSTRUCTURAL CHANGES OF THYROID FOLLICLES IN HYPERTHYROIDISM. (2025). International Journal of Political Sciences and Economics, 4(11), 294-297. https://doi.org/10.55640/

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