COMPREHENSIVE STUDY OF GASTRITIS. ETIOLOGY, PATHOGENESIS, CLINICAL MANIFESTATIONS, AND MODERN THERAPEUTIC STRATEGIES
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Abstract
This extensive scientific research is dedicated to one of the most pressing issues in modern gastroenterology—inflammatory-dystrophic diseases of the gastric mucosa. The article provides a profound analysis of the complex etiopatogenesis of gastritis, the molecular-level role of Helicobacter pylori infection in its development, as well as the interrelationship between dietary factors, exogenous toxic influences, and endogenous autoimmune processes. It highlights the specific characteristics of clinical manifestations arising from regional dietary habits, socio-psychological stress factors, and the uncontrolled use of medications among the population of Uzbekistan. The diagnostic significance of modern high-tech methods, including high-definition video endoscopy and histomorphological examinations according to the "Sydney" system, is scientifically substantiated. In the treatment section, the effectiveness of eradication therapy is analyzed based on the international "Maastricht VI" consensus and local clinical protocols. The study concludes with a complex set of recommendations for preventing the transition of the disease into a chronic form, gastric cancer prophylaxis, and improving the quality of life for patients.
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