MYOCARDIAL HEART DISEASE
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Abstract
Pathologies of the Myocardium: Pathophysiology, Classification, and Clinical Consequences This summary addresses the pathologies of the myocardium—the muscular layer of the heart responsible for its pump function. Myocardial diseases are classified based on their underlying etiological and pathophysiological mechanism: ischemic (e.g., myocardial infarction, leading to necrosis and scarring), inflammatory (myocarditis, characterized by immune infiltration and fibrosis), and primary structural (cardiomyopathies—dilated, hypertrophic, restrictive), often with a genetic origin. All these pathological processes inevitably lead to impaired systolic or diastolic function, resulting in the development of Chronic Heart Failure (CHF), arrhythmias (including sudden cardiac death), and thromboembolic complications. Diagnosis requires a comprehensive approach utilizing specific biomarkers (troponins) and imaging modalities (Echocardiography, Cardiac MRI).
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